Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Evaluation of the pharmacokinetics for [14C]-benzo[a]pyrene ([14C]-BaP) and metabolites in
plasma and urine over 48 hours following a 50 ng dose (5.4 nCi) alone, following 7 days'
consumption of Brussels sprouts, and following 7 days' consumption of a supplement containing
3,3'-diindolylmethane (DIM).
Phase:
Early Phase 1
Details
Lead Sponsor:
Oregon State University
Collaborators:
Lawrence Livermore National Laboratory National Institute of Environmental Health Sciences (NIEHS) Pacific Northwest National Laboratory